{"id":7331,"date":"2015-11-23T14:54:25","date_gmt":"2015-11-23T20:54:25","guid":{"rendered":"https:\/\/wholehealthchicago.com\/?p=7331"},"modified":"2021-10-17T09:59:58","modified_gmt":"2021-10-17T14:59:58","slug":"hpv-immunization-mired-in-controversy","status":"publish","type":"post","link":"https:\/\/wholehealthchicago.com\/blog\/2015\/11\/23\/hpv-immunization-mired-in-controversy","title":{"rendered":"HPV Immunization: Mired In Controversy"},"content":{"rendered":"\n<p>Patients with pre-teens and teenagers have been asking my opinion on the HPV (human papilloma virus) immunization, sold as Gardasil by the <a href=\"https:\/\/wholehealthchicago.com\/blog\/2011\/08\/02\/more-sleaze-from-big-pharma\" target=\"_blank\" rel=\"noreferrer noopener\">Big Pharma<\/a> giant Merck. Young daughters, and now sons, are bringing home handouts from school, being pressured by the family pediatrician, and, oh those TV commercials.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-4-3 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"GARDASIL TV Commercial\" width=\"770\" height=\"578\" src=\"https:\/\/www.youtube.com\/embed\/15Jk3OBm3lU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>Families who go online discover arguments for and against immunization that sound like two dogs on opposite sides of a cyclone fence barking furiously at each other. Actually, that\u2019s an unfair comparison. Most of the scientists on both sides are fairly reserved, but you can sense their dismay that the view of their side hasn\u2019t been accepted as universal truth.<\/p>\n\n\n\n<p>\u201cWhy in heaven\u2019s name would you not want to use a safe vaccine to protect your children from certain cancers that could kill them,\u201d says one group of well-meaning (and generally Big Pharma-funded) scientists. The other side responds \u201cBecause we aren\u2019t positive that the vaccine is safe, that it really does protect against cancer, and that the long-term effects are harmless.\u201d<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>As a parent, your most sane conclusion is confusion<\/strong><\/h3>\n\n\n\n<p>Regular readers of these Health Tips know that I\u2019m highly skeptical of virtually all clinical trials and research studies testing any industry-funded pharmaceutical product simply because there\u2019s so much money involved in terms of Big Pharma profits. Look at the following Gardasil numbers and prepare for a throbbing head trying to get a handle on the math.<\/p>\n\n\n\n<p>The three Gardasil injections come to about $600, generally funded through health insurance and various government subsidies. <a href=\"https:\/\/www.cdc.gov\/vaccines\/hcp\/vis\/vis-statements\/hpv-gardasil.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">Current CDC recommendations call for Gardasil to be given to all girls and boys between 11 and 12.<\/a> This is for the US, but Gardasil is marketed worldwide (or at least in those areas of the world that can afford it). My pocket calculator can\u2019t handle this, but let\u2019s agree that Merck, which manufactures Gardasil, stands to make a lot of money. Along the way, Merck can also afford to pay its researchers, especially those who bring in good results, a great deal of money.<\/p>\n\n\n\n<p>Before you have your daughter or son thrice jabbed by the pediatrician, consider:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>HPV is the most common sexually transmitted disease (STD). There are about 100 strains of HPV (some strains cause those harmless warts you had as a kid), but only a few, like #16 and #18, are linked to cervical cancer.<\/li><li>Most HPV infections go away by themselves. The higher-risk strains take years to develop into cervical cancer.<\/li><li>Gardasil does confer immunity against nine of the high-risk HPV types, but no one (not even Merck) knows exactly how long this immunity lasts. The best guess is that booster shots will be needed every four years.<\/li><\/ul>\n\n\n\n<p>There has been controversy about the phrasing used by Merck researchers. The ads say \u201cHelps prevent HPV infection\u201d and \u201cexpected to prevent cervical cancer\u201d but this is not the same as \u201cdefinitely prevents cervical cancer.\u201d WebMD says that Merck now reports Gardasil does prevent cancer. In the same breath WebMD admits that Merck is a financial supporter of WebMD (get my drift?).<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Deaths from cervical cancer are not all that common<\/strong><\/h3>\n\n\n\n<p>This year there will be 12,000 new cases of cervical cancer (discovered by Pap smears) and most women will be completely cured. 4,000 American women will die from cervical cancer, compared to 40,000 women dying from breast cancer and 25,000 from colon cancer.<\/p>\n\n\n\n<p>Deaths occur primarily in women who have never had a Pap smear and arrive at the doctor with advanced disease. In fact most cervical cancer deaths occur among <a href=\"https:\/\/www.cancer.gov\/about-nci\/organization\/crchd\/cancer-health-disparities-fact-sheet#q7\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">medically underserved women of color<\/a>. As the article at the link states, \u201cNCI conducted a study of regions within the United States where cervical cancer incidence rates are high. They found that cervical cancer rates reflected a larger problem of unequal access to health care.\u201d Death rates are even higher in underdeveloped countries.<\/p>\n\n\n\n<p>Although most female patients at WholeHealth Chicago have their own gynecologists for Pap smears, we do quite a few ourselves and in 16 years we\u2019ve never had a single Pap smear that&nbsp;revealed cervical cancer. A few patients have <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/cervical-cancer\/expert-answers\/cervical-dysplasia\/FAQ-20058142\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">cervical dysplasia<\/a>, some cases of which increase cancer risk, though most do not. This low incidence of cancer is the result of access to care, regular checkups, and healthy lifestyles.<\/p>\n\n\n\n<p><u>Take-home message<\/u>: get your annual Pap smear (and to protect against all STDs, HPV included, use a condom). You\u2019ll be tested for HPV during your Pap smear and if you\u2019re negative you can reduce the frequency of annual Pap smears to every three years for women between 21 and 30, and every five years between 31 and 65.<\/p>\n\n\n\n<p>Gardasil is probably a good idea in those US regions (and other countries) where women don\u2019t have access to Pap smears or don\u2019t get them regularly for other reasons. However, until there\u2019s better data on actual cancer prevention (like the results of tracking immunized vs. non-immunized girls), I recommend not rushing into this. One fear is that once immunized, women might not be as stringent about getting their annual exams\u2014a definite mistake as the pelvic exam done with a Pap smear can diagnose a variety of conditions unrelated to cervical cancer (including ovarian cancer, fibroids, and endometriosis).<\/p>\n\n\n\n<p>Then, of course, there\u2019s always the question of safety. Is the Gardasil three-shot immunization series completely safe? Naturally, Merck says yes and that the most commonly reported side effects (lightheadedness, fainting, and pain at the injection site) are harmless events that occur with many young girls receiving any type of an injection. These complaints are being reported at a frequency no different from when the young girls are injected with a placebo.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>But we should be skeptical<\/strong><\/h3>\n\n\n\n<p>It often takes years for serious issues related to any new medication to appear. For example, the permanent tendon damage that can occur with quinolone antibiotics (like Cipro and Levaquin) wasn\u2019t reported until the drug had been out for several years. No one ever connected an antibiotic with tendon inflammation. Now, 30 years later, tendon damage is such a risk that there\u2019s a black box warning (high risk, dangerous) printed on the package insert.<\/p>\n\n\n\n<p>What caught my eye about Gardasil was a series of reports from around the world that told of a syndrome appearing in young women who had received the Gardasil vaccination. The symptoms seemed indistinguishable from the fibromyalgia\/chronic fatigue syndrome I\u2019ve been working with for years.<\/p>\n\n\n\n<p>\u201cOi veh!\u201d I mumbled to myself. \u201cWe need this vi ein loch in kopf.\u201d I will translate. \u201cOh woe! We need this like we need a hole in the head.\u201d<\/p>\n\n\n\n<p>As if teenagers didn\u2019t have enough tsuris (troubles) with pimples, hormones, bullies, and getting into the college of their parents\u2019 choice, now we\u2019re going to give them fibromyalgia? Chronic fatigue?<\/p>\n\n\n\n<p>Other reported symptoms include orthostatic hypotension (fainting when rising from a seated to a standing position, also called postural orthostatic tachycardia syndrome, or POTS), complex regional pain syndrome (CRPS, a horror show of constant and difficult-to-relieve pain in one specific limb), memory and cognitive problems, sleep disorders, and so forth.<\/p>\n\n\n\n<p>Or you could simply watch <a href=\"https:\/\/www.youtube.com\/watch?v=6UHy-EkK2xo\" target=\"_blank\" rel=\"noopener\">one teenage girl describing her li<\/a><a href=\"https:\/\/www.youtube.com\/watch?v=6UHy-EkK2xo\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">f<\/a><a href=\"https:\/\/www.youtube.com\/watch?v=6UHy-EkK2xo\" target=\"_blank\" rel=\"noopener\">e after Gardasil<\/a>, though I\u2019ll be the first to acknowledge that it\u2019s possible she could have developed these symptoms without Gardasil. Certainly most fibro-CFS patients have no history of using Gardasil. Warning: the video at the link is emotionally wrenching and I notice there are at least a dozen others.<\/p>\n\n\n\n<p>Naturally, those involved in the promotion of Gardasil stand by their guns, saying basically that such symptoms can appear in anyone and that the frequency of fibromyalgia-chronic fatigue in those who have been vaccinated with Gardasil is no different than in the female population at large. The European Medical Agency (EMA) reassures EU patients and physicians not to worry, but the EMA has real issues with financial conflicts of interest.<\/p>\n\n\n\n<p>Some countries are very concerned, not thrilled about trading protection from a low-risk virus for a lifetime of pain, fatigue, and disability. In 2013, Japan withdrew its Gardasil recommendations to the public and initiated a system for physicians to report on side effects. <a href=\"https:\/\/www.danmedj.dk\/portal\/page\/portal\/danmedj.dk\/dmj_forside\/PAST_ISSUE\/2015\/DMJ_2015_04\/A5064\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">After a study was published in Denmark about the link between Gardasil, POTS and CRPS<\/a>, the Danish government ordered its own independent study, separate from the bland reassurances of Merck and the EMA. Glaxo (a second vaccine manufacturer) vehemently denies everything and I\u2019d link you to their article but it\u2019ll cost you $35 to read it.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>So there it is<\/strong><\/h3>\n\n\n\n<p>You\u2019ve got a kid at home who\u2019s soon going to be flooded with sex hormones and you don\u2019t want her or him to develop cancer related to sexual activity. (For men, BTW, it\u2019s prevention of penis cancer, which is rare in North America. I saw it just once in my career at Cook County Hospital in an elderly, malnourished skid row alcoholic.)<\/p>\n\n\n\n<p>You\u2019ve got a pharmaceutical industry with one goal: shareholder profits. Their track record for manipulating clinical trials and withholding information about side effects is shameful.<\/p>\n\n\n\n<p>If your health insurance covers regular Pap smears for your daughter and she is getting them, your son or daughter is clear that a condom must always be used to prevent STD transmission, and your daughter doesn\u2019t smoke (yet another risk), well, make the best decision you can.<\/p>\n\n\n\n<p>Be well,<br><em>David Edelberg, MD<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Patients with pre-teens and teenagers have been asking my opinion on the HPV (human papilloma virus) immunization, sold as Gardasil by the Big Pharma giant Merck. Young daughters, and now sons, are bringing home handouts from school, being pressured by the family pediatrician, and, oh those TV commercials. Families who go online discover arguments for [&hellip;]<\/p>\n","protected":false},"author":2087,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,195,67,3],"tags":[1809,1810,1811,1812,1813,1518],"class_list":["post-7331","post","type-post","status-publish","format-standard","hentry","category-blog","category-diseases","category-h","category-knowledge-base","tag-cervical-cancer","tag-cervical-dsyplagia","tag-gardasil","tag-hpv-immunization","tag-human-papilloma-virus","tag-pap-smear"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\r\n<title>HPV Immunization: Mired In Controversy<\/title>\r\n<meta name=\"description\" content=\"The three Gardasil injections come to about $600, generally funded through health insurance and various government subsidies.\" \/>\r\n<meta name=\"robots\" content=\"index, follow, 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