{"id":32256,"date":"2026-06-01T21:50:34","date_gmt":"2026-06-02T02:50:34","guid":{"rendered":"https:\/\/wholehealthchicago.com\/blog\/?p=32256"},"modified":"2026-06-01T21:50:38","modified_gmt":"2026-06-02T02:50:38","slug":"could-skinny-shots-cure-fibromyalgia","status":"publish","type":"post","link":"https:\/\/wholehealthchicago.com\/blog\/2026\/06\/01\/could-skinny-shots-cure-fibromyalgia","title":{"rendered":"COULD \u201cSKINNY SHOTS\u201d CURE FIBROMYALGIA?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The most well-known, so-called \u2018skinny shots\u2019 are semaglutide and tirzepatide. the GLP-1 inhibitors may be better known by their heavily advertised brand names Ozempic (semaglutide), Mounjaro (tirzepatide), and Zepbound (also tirzepatide). If it seems like \u2018everybody\u2019s on them,\u2019 you\u2019re right. Currently 18% of the U.S. population report having used a GLP-1 inhibitor at some time in their lives.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you\u2019ve not tried a GLP-1, the med works by balancing your blood sugar, slowing your digestion, and preventing you from feeling hunger. You literally forget to eat. You don\u2019t hear any background \u201cfood noise,\u201d no inner voice whispering (or screaming) \u201cfeed me that bag of potato chips, now!\u201d And then, slowly, steadily, at about a pound a week, you lose weight.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">With millions of patients on GLP-1 inhibitors, doctors began noticing side benefits. Many patients with autoimmune diseases like rheumatoid arthritis, inflammatory bowel disease, psoriasis, multiple sclerosis, and lupus remarked about feeling \u2018better.\u2019 Although the GLP-1\u2019s are not FDA approved for any of these conditions, many specialists are using them as \u2018add-on\u2019s\u2019 to conventional therapies. The science behind this is that at the heart of every autoimmune disease is an excess of an inflammatory molecule called a pro-inflammatory cytokine. These are literally \u201cpacked\u201d into fat cells. The levels of cytokines are measured by blood tests hsCRP (high sensitive C-Reactive Protein), TNF (Tumor Necrosis Factor), and IL-6 (interleukin-6). High levels of each trigger inflammation and pain.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">I have been working with fibromyalgia patients for thirty years. The condition affects about 4% of the population, 90% female, and to this day it is considered a \u201cclinical diagnosis\u201d based on listening to your patient and performing a physical exam. There are no \u201ctests\u201d for fibromyalgia. \u2018Fibro\u2019 is not an autoimmune disease but does seem to be an overreaction of the nervous system to \u2018pain signals.\u2019<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">However, using the GLP-1 medications during the past two years has brought some extremely interesting results.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>It had been known from previous research that the severity of a patient\u2019s fibromyalgia correlated to her body fat distribution especially as fat cells infiltrated through her muscles.<\/li>\n\n\n\n<li>Women have much more fatty tissue throughout their bodies and more visceral fat (deep in abdominal cavity), literally a storehouse of inflammatory chemicals.<\/li>\n\n\n\n<li>Women frequently describe themselves as \u201cfeeling inflamed.\u201d Well, they are.<\/li>\n\n\n\n<li>And yet, despite being awash with inflammatory cytokines, fibromyalgia patients routinely test negative for having any autoimmune disease.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Having a special interest in fibromyalgia, and having written \u201cHealing Fibromyalgia,\u201d we\u2019ve accumulated quite a few fibro patients over the past three decades. Our patient population follows the national statistics: 90% female, 80% overweight or obese.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Many have started GLP-1 meds.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">You can guess where this is going. Those that have lost the most weight, emptying their muscles of inflamed fat cells, have also had the best success with their fibromyalgia.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This totally concurs with a recent study published <a href=\"https:\/\/www.theeducatedpatient.com\/view\/glp-1-medications-may-reduce-pain-and-fatigue-in-pat%20ients-with-fibromyalgia\">here.<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The main problem of course, is that unless you\u2019re \u2018obese\u2019 (BMI &gt;30) or diabetic, your insurance likely won\u2019t cover a GLP-1. Fortunately, the government allows compounding pharmacies to prepare the syringes and you can start treatment by scheduling with your WholeHealth Chicago practitioner.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Be well,<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">David Edelberg, MD<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The most well-known, so-called \u2018skinny shots\u2019 are semaglutide and tirzepatide. the GLP-1 inhibitors may be better known by their heavily advertised brand names Ozempic (semaglutide), Mounjaro (tirzepatide), and Zepbound (also tirzepatide). If it seems like \u2018everybody\u2019s on them,\u2019 you\u2019re right. Currently 18% of the U.S. population report having used a GLP-1 inhibitor at some time [&hellip;]<\/p>\n","protected":false},"author":2087,"featured_media":32257,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[209,296,27],"tags":[2673,208,2700,49],"class_list":["post-32256","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fibromyalgia-chronic-fatigue","category-inflammation","category-weight-issues","tag-cytokines","tag-fibromyalgia","tag-glp-1-ra","tag-weight-loss"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\r\n<title>COULD \u201cSKINNY SHOTS\u201d CURE FIBROMYALGIA? - WholeHealth Chicago<\/title>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/wholehealthchicago.com\/blog\/2026\/06\/01\/could-skinny-shots-cure-fibromyalgia\" \/>\r\n<meta property=\"og:locale\" content=\"en_US\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"COULD \u201cSKINNY SHOTS\u201d CURE FIBROMYALGIA? - WholeHealth Chicago\" \/>\r\n<meta property=\"og:description\" content=\"The most well-known, so-called \u2018skinny shots\u2019 are semaglutide and tirzepatide. the GLP-1 inhibitors may be better known by their heavily advertised brand names Ozempic (semaglutide), Mounjaro (tirzepatide), and Zepbound (also tirzepatide). If it seems like \u2018everybody\u2019s on them,\u2019 you\u2019re right. 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