{"id":15711,"date":"2019-05-13T12:37:50","date_gmt":"2019-05-13T17:37:50","guid":{"rendered":"https:\/\/wholehealthchicago.com\/?p=15711"},"modified":"2021-07-24T00:37:25","modified_gmt":"2021-07-24T05:37:25","slug":"epstein-barr-virus-ebv-trouble-on-the-horizon","status":"publish","type":"post","link":"https:\/\/wholehealthchicago.com\/blog\/2019\/05\/13\/epstein-barr-virus-ebv-trouble-on-the-horizon","title":{"rendered":"Epstein-Barr Virus (EBV): Trouble On The Horizon"},"content":{"rendered":"\n

A quick blood test will verify that 98% of you are carrying an inactive form of Epstein-Barr virus (EBV<\/a>), one of several herpesviruses (human herpesvirus 4, to be exact) that can rest quietly in your body.<\/p>\n\n\n\n

You hope.<\/p>\n\n\n\n

That high percentage is confirmed by testing large populations for the presence of EBV antibodies, produced by the immune system in response to the presence of a foreign substance. I well remember a medical school professor saying, \u201cEverybody has them.\u201d<\/p>\n\n\n\n

EBV is not the same herpes as the villain of cold sores (herpes simplex 1) or genital herpes (herpes simplex 2). EBV is a cousin to the herpes virus that causes chickenpox (the varicella-zoster virus), which can lie dormant for years and then appear as shingles.<\/p>\n\n\n\n

As you\u2019re reading this Health Tip, all but 2% of you carry EBV as a fellow traveler, nestling inside billions of your cells. And while you needn\u2019t lie in bed at night plaintively asking \u201cWhy me?\u201d you\u2019ll soon learn that EBV, tiny as it is, merits your attention and respect. It\u2019s a potential troublemaker.<\/p>\n\n\n\n

First, let\u2019s talk about how you got it
<\/strong>Once upon a time you were a horny adolescent, coping with the rising tides of either estrogen or testosterone. You met that seriously cute whatever-your-preference, engaged in some deep kissing, and a few days or weeks later noticed respiratory symptoms that ranged from an uncomfortable scratchy throat to full-fledged mono (infectious mononucleosis, also called the \u201ckissing disease\u201d) with fever, a really painful throat, swollen lymph glands in your neck, and exhaustion like you\u2019d never felt in your life.<\/p>\n\n\n\n

You may have been a student and had to drop out for a semester, but then, slowly, you did manage to recover.<\/p>\n\n\n\n

Just about everyone who\u2019s had mono, mild or severe, recovers uneventfully. But there is a small population that can date their lifetime of chronic fatigue to their mono. In fact, for a while the original chronic fatigue syndrome (also called myalgic encephalomyelitis) was attributed solely to EBV. However, when everyone, including doctors themselves, began testing positive for EBV, researchers took it off the table of chronic fatigue suspects.<\/p>\n\n\n\n

They then made two errors, which they\u2019ve thankfully reversed. First, since no test can diagnose chronic fatigue, they decided that patients were hypochondriacs and wrote it off as the yuppie flu. It\u2019s a common and regrettable ploy: if you can\u2019t make a diagnosis, then somehow twist it around and blame the patient (\u201cSee a psychiatrist\u201d).<\/p>\n\n\n\n

Second, they wrote off all those EBV antibodies as completely harmless, evidence of the immune system\u2019s prowess, positing that once your acute EBV infection was behind you, you\u2019d never be bothered again.<\/p>\n\n\n\n

Word also spread among the healthcare profession that no one could get mono twice. The presence of EBV antibodies was thought to be an immunization against future EBV infections.<\/p>\n\n\n\n

More to EBV than meets the eye
<\/strong>But evidence mounted that there was more to EBV. The bodies of one small group of people, mainly of Asian extraction, were overwhelmed by EBV and without major treatment, such as bone marrow transplants, many died. This condition is called chronic active Epstein Barr (CAEB)<\/a> and classified as a rare disease, which fortunately it is.<\/p>\n\n\n\n

Later, EBV began to be linked with a host of other problems. Some were truly debilitating (causing fatigue, muscle aches, fever, etc), indistinguishable from chronic fatigue syndrome, with no chance for positive test results except those pesky and persistent EBV antibodies.<\/p>\n\n\n\n

Researchers have proposed that for some genetically predisposed people, chronic fatigue syndrome is caused by reactivation of dormant EBV. There are, of course, other known causes of chronic fatigue including chronic Lyme, toxic metal exposure, and mold exposure, but reactivated EBV is high on the list.<\/p>\n\n\n\n

Reactivated EBV
<\/strong>And then, quite spookily, the list of conditions associated with reactivated EBV began to grow.<\/p>\n\n\n\n

For example: multiple sclerosis<\/a>, Parkinson\u2019s<\/a>, and a whole slew of autoimmune diseases<\/a>, including lupus, rheumatoid arthritis, scleroderma, ulcerative colitis\/Crohn\u2019s, and Hashimoto\u2019s thyroiditis<\/a>, and an equally frightening list of cancers<\/a> (Hodgkins disease, non-Hodgkin\u2019s lymphoma, nasopharyngeal carcinoma, stomach cancer). Even breast cancer<\/a> and cervical cancer<\/a>.<\/p>\n\n\n\n

With so many apparently unrelated conditions, maybe that dormant EBV isn\u2019t so dormant after all.<\/p>\n\n\n\n

The pharmaceutical industry has not yet developed an antiviral medication that works against acute EBV (mono) and there\u2019s no vaccine on the horizon. We\u2019ve got safe and effective antivirals against herpes simplex (cold sores, genital herpes), HSV (shingles), influenza, and even HIV, but nothing consistently effective against EBV<\/a>. As a result, researchers are focusing on the triggers that reactivate dormant EBV and convert it to disease.<\/p>\n\n\n\n

What those triggers are and how you can safely keep your personal EBV in check (because, sorry, but you probably have it inside you somewhere) will be the subject of next week\u2019s Health Tip.<\/p>\n\n\n\n

Be well,
David Edelberg, MD<\/p>\n","protected":false},"excerpt":{"rendered":"

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