2265 North Clybourn Avenue    Chicago, IL 60614    P: 773.296.6700     F: 773.296.1131

Poisoned by an Antibiotic

Posted 3/16/2010

Although he was only in his early thirties, he moved like an old man with widespread arthritis. At the stairs, he supported himself on the short banister to keep his full weight off his feet. It looked as if every one of his muscles were in pain.

Inside his chart, in the section where he’d written his reason for the appointment were the words, “Poisoned by Levaquin.” He was the fourth such patient I’d seen in the past year or so.

Levaquin (generic name: levofloxacin) is the best-seller among antibiotics in the fluoroquinolone class (“floxins,” for short). Others include Cipro and Avelox. Still others you’ve never heard of because they’ve been yanked by the FDA for excessively dangerous side effects including heart, brain, and nerve damage. Because of these potential side effects, the general recommendation to doctors has been to use floxins only when absolutely necessary, choosing milder antibiotics (like Z-Pak or Augmentin) whenever possible.

But both doctors and patients like the floxins. They’re fast, effective, conveniently dosed at one per day, and generally reliable for difficult infections like sinusitis. For most users, they are safe. The floxins are so widely used in their various forms–intravenous, oral, even eye and eardrops–that hospital residents refer to Levaquin as “Vitamin L.” An important aside: this overuse has led to more cases of hospital acquired MRSA (methicillin resistant staph infection) and C. Difficile (hard-to-treat diarrhea) than other antibiotics. At a recent WholeHealth Chicago staff meeting, half of us, including me, acknowledged having taken a floxin at least once in our lives, and we all generally avoid drugs.

Why it took so long to recognize that the floxins could destroy a person’s tendons is understandable. No one ever dreamed that tendonitis (inflammation of the rope-like tissue that attaches muscles to bones) could be caused by an antibiotic, or by any drug for that matter. Antibiotics routinely cause nausea, vomiting, diarrhea, skin rashes, and yeast infections, and every doctor knows this.

But when some people started suffering painful tendons during, or shortly after, taking a floxin drug, they didn’t connect the two and most didn’t mention it to their doctors. When it was mentioned, doctors didn’t make the connection either and often continued the antibiotic, adding an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen for the tendonitis, which we now know made matters worse.

The red flag on the floxins and tendonitis came up during “post marketing surveys” and letters to the FDA from doctors who did see the connection. Post marketing surveys are the bane of the pharmaceutical industry, which doesn’t really want to hear any bad news about its drugs. Historically, companies have minimized post-marketing data (just like Toyota is doing now), holding off as long as possible reporting their concerns to the FDA. After all, there’s serious money involved.

But more and more patients taking floxins began reporting tendonitis symptoms, especially when walking. Their pain usually started in the Achilles tendon at the back of the calf and then occasionally spread throughout the body, sometimes becoming indistinguishable from fibromyalgia, except that with fibro, the Achilles tendons are virtually never affected. Why the Achilles first? Probably because they’re the most heavily used–every step you take stretches and relaxes these tendons. Interestingly, the three people I’ve treated with this condition were all heavy users of their Achilles (hikers, cyclists, and basketball players).

In susceptible people, floxins can seriously damage the tendons. Several cases of spontaneous Achilles rupture (complete tear) have been reported, and during repair surgery the affected tendon tissue appears unhealthy and heals poorly. In some patients, tendon damage is permanent. Their lives are changed forever, and they suffer chronic daily pain after just a week on a floxin for something minor, like an annoying sinus infection. Fortunately, permanent tendon damage is uncommon. But full recovery can be very slow.

None known. Diagnostic tests? No tests comes up “positive” and therefore some patients are dismissed as neurotic. There is no cure. On the plus side, when the tendonitis is mild, it usually goes away by itself, often after a month or two. Severe cases are disabling and several class action lawsuits are currently underway. You can bet the defense attorneys for Big Pharma are delighted the floxins cause no positive tests and will play the neurotic card to the hilt. I suspect the plaintiffs would be happy to drop all charges if they could have their lives back.

At WholeHealth Chicago, we treat floxin toxicity using natural products to enhance the patient’s own detoxifying systems. Floxin-tendonitis victims have a history of sensitivities to a wide variety of chemicals and drugs, indicating sluggish detox mechanisms. We advise patients to start an anti-inflammatory eating program and take natural anti-inflammatory supplements, such as fish oil and boswellia. We also refer patients to our homeopath. Floxin patients are so drug-sensitive that I’m reluctant to prescribe any conventional drug, feeling comfortable only with the safe and gentle remedies of homeopathy.

• Essentially, all drugs are potentially poisonous chemicals. Please read that aloud, twice. As a small amount of chemical courses through your body, it has the potential to affect every single organ, for better or worse. The chemical’s single positive effect becomes its (heavily marketed) clinical use and can be worth billions in revenue. The chemical’s numerous bad effects (some obvious, others subtle, all euphemistically called side-effects) are diligently swept under the rug, mostly ignored by the pharmaceutical industry and the FDA, overlooked by the prescribing physician, and a source of endless but often well-founded concern to the patient.

• If you do need a drug, ask about the oldest rather than the latest. If you’re not allergic to sulfa drugs, for example, for sinus and urinary infections these have been around for more than 70 years and the side effects are known and familiar. If your doctor suggests a floxin drug, tell her you’ve read about them and would prefer a milder antibiotic.

• When you start on a drug, read the side-effect list. A rule of thumb I learned in medical school: if a patient arrives with a new and unexplained symptom and has started on a new drug, regardless the symptom investigate the drug first, not last.

• If you’re generally a chemically sensitive person (you know who you are), take all steps to avoid prescription drugs. If there’s no alternative, start with a pediatric dose. It will probably work fine for you.

• Most drugs are prescribed to cover you for years of unhealthful lifestyle choices (diabetes, heart disease, acid reflux, emphysema, etc). Others are for conditions you could treat in safer ways (neti pot for sinus infections, St. John’s wort and counseling for depression). Most drugs work much less well than anyone (doctors, patients, even Big Pharma) likes to consider. In their heart of hearts, doctors bank heavily on the placebo effect.

I’ll leave you with this unsettling fact: It’s estimated that correctly administered and correctly taken prescription drugs are the fourth leading cause of death in the US.

  1. Diane Engelhardt says:

    Trying to find a reason for my foot pain. Didn’t start in Achilles but getting worse. Have numbness in toes from chemo including Avastin trial for 1 year. Ugh! It’s getting worse…

  2. ber says:

    Thank u for this article. The pieces of my myriad health issues is coming together and we think this may be a root cause, along with methylation errors. It’s upsetting that there is no true treatment and the prognosis seems dim. Do u find that people are able to regain their quality of life, or is this a degenerative thing that progressively gets worse? Also, what other body systems are affected, bc if I’m not mistaken, isn’t the damage fairly widespread to other body systems (gut, endocrine, nervous system, etc)?


Join our Newsletter

Get health recommendations, delicious and time-saving recipes, medical news, supplement reviews, birthday discounts, and more!


Health Tips

Dr. Edelberg’s Health Tips contain concise bits of advice, medical news, nutritional supplement and pharmaceutical updates, and stress relief ideas. With every Health Tip, you’ll also receive an easy, delicious, and healthful recipe.

When you sign up to receive Health Tips, you can look forward to Dr. Edelberg’s smart and very current observations arriving in your in-box weekly. They’re packed with helpful information and are often slightly irreverent. One of the most common responses to the tips is “I wish my doctor talked to me like this!”

Quick Connect

Get One Click Access to our


The Knowledge Base

Patient education is an integral part of our practice. Here you will find a comprehensive collection of staff articles, descriptions of therapies and nutritional supplements, information addressing your health concerns, and the latest research on nutritional supplements and alternative therapies.

Telemedicine – Now Available at WholeHealth Chicago

In order to maintain your continuity of care, WholeHealth Chicago now offers telemedicine appointments with most of our practitioners. During a telemedicine visit, you and your healthcare provider can review medical history, discuss symptoms, arrange for prescriptions, and more. When necessary, labs and diagnostic imaging can be ordered from a facility near your home, and our Natural Apothecary can ship supplements quickly to your door.

Please contact Patient Services for details and scheduling a telemedicine appointment, or to change a regular appointment to telemedicine by calling 773-296-6700.

We’re looking forward to meeting with you in our virtual consultation room soon.

Upcoming Workshops

**Adrenal Boost!
Tue, April 28, 6:00 PM – 8:00 PM
With Naturopath Caley Scott and Yoga Therapist Renee Zambo

Course Fee: $75.00
(Includes custom adrenal herbal tincture and a description of yoga practices you can do at home.)

Feeling Tired? Need help improving fatigue? Learn to boost your energy! Dr. Scott will teach you about herbs that support your adrenal glands to help boost your energy and adapt to stress. Renee will teach practices that restore and build energy, support daily activities, and ensure sound rest at night. More →

Recent Health Tips

  • Coronavirus Immune Superstar #1: Vitamin D

    Take 5000 IU daily. Here’s why: • The role of vitamin D in the human body is complex, with ramifications well beyond healthy bones. One of D’s effects is to trigger your immune system into a high-alert, anti-viral state. • Low Vitamin D increases your susceptibility to viral infections, likely including Covid-19. Former CDC director Tom Frieden has publicly stated that vitamin D may protect Read More

  • Important: High-Dose Vitamin C

    Look. I know you’re crazy busy at home, sheltering in place, sleeping a lot, eating too many carbs, binging marginal TV, and generally going bonkers. You don’t have a lot of spare time. But please click to this article in the New York Post. Too busy for that? OK. I’ll summarize. Intravenous vitamin C in high doses is being used both in China and in Read More

  • Taking Care of Yourself while Staying Home

    Seeing Your Chiropractic Physician via Telemedicine? Absolutely! I know what you’re thinking. ‘How can you possibly give me an adjustment during a video conference?’  The short answer is I can’t, but when coming to our office for an in-person appointment is difficult or impossible, I can continue to help. As a chiropractic physician, I’ve been working with patients via telemedicine for several years, and it’s Read More

Join our Discount Program

Member benefits include 10% off all your purchases. Low, one-time membership fee of $25 ($35 for family).


Join our Newsletter

Get health recommendations, recipes, medical news, supplement reviews, birthday discounts, and more!