2265 North Clybourn Avenue    Chicago, IL 60614    P: 773.296.6700     F: 773.296.1131

Melatonin and Perimenopause

I was surprised to see a clinical report using the nutritional supplement melatonin in the Annals of the New York Academy of Science, simply because it’s a very conservative journal, rarely acknowledging the existence of natural medicine.

Your body produces melatonin, the sleep hormone, when your brain is stimulated by darkness. Melatonin is made in the following sequence:

  • Tryptophan, an amino acid (one of the building blocks of protein-rich foods) undergoes a conversion to
  • 5-Hydroxytryptophan (5-HTP), which goes on to convert to
  • Serotonin, and then into
  • Melatonin

You can see how any situation where your feel-good serotonin is low causes melatonin to be low as well. This may be one of the reasons why some people who are depressed sleep poorly, and why taking a natural or prescription antidepressant to raise serotonin often helps sleep problems.

But serotonin is also linked closely to estrogen, so closely that in any situation in which your estrogen falls–such as during PMS days or perimenopause–your serotonin levels drop too. This can result in the irritability of PMS and the depression/anxiety that sometimes accompany perimenopause.

Back to the Annals article: researchers measured blood amounts of melatonin in perimenopausal women and (because melatonin levels are closely linked to estrogen and serotonin) found low melatonin levels.

And then they asked: What would happen if these perimenopausal women took melatonin as a supplement? The surprising result was a virtual reversal of certain aspects of the aging process.

The melatonin acted on the pituitary gland (your body’s master gland) to stimulate the ovaries and thyroid to act “younger.” Women reported less depression, better sleep, more energy, and even, for some, a return of regular menstrual cycles.

Melatonin has been around for years and is quite safe. Reflect on this very interesting study and if you want to try melatonin for perimenopausal-related depression, fatigue, or insomnia, you can order the melatonin I use in my practice by clicking here. The dose recommended in the study was 3 mg, taken at bedtime.


Join our Newsletter

Get health recommendations, delicious and time-saving recipes, medical news, supplement reviews, birthday discounts, and more!

BIRTHDAY

Health Tips

Dr. Edelberg’s Health Tips contain concise bits of advice, medical news, nutritional supplement and pharmaceutical updates, and stress relief ideas. With every Health Tip, you’ll also receive an easy, delicious, and healthful recipe.

When you sign up to receive Health Tips, you can look forward to Dr. Edelberg’s smart and very current observations arriving in your in-box weekly. They’re packed with helpful information and are often slightly irreverent. One of the most common responses to the tips is “I wish my doctor talked to me like this!”

Quick Connect

Get One Click Access to our

patient-portal

The Knowledge Base

Patient education is an integral part of our practice. Here you will find a comprehensive collection of staff articles, descriptions of therapies and nutritional supplements, information addressing your health concerns, and the latest research on nutritional supplements and alternative therapies.

Join our Newsletter

Get health recommendations, recipes, medical news, supplement reviews, birthday discounts, and more!

Upcoming Workshops


**Winter Solstice Celebration: An evening of Acupuncture and Shamanic Healing
Tuesday, December 17, 5:45–7:30pm
Hosted by Katie Oberlin, HTCP and Mari Stecker, LAc

Course Fee: $75.00

Take a break from the hustle and bustle of the holiday season to enter the stillpoint of the Winter Solstice, reflect on the lessons of 2019, and set intentions for the new year. This will be an evening of individual and group healing, ceremony, and celebration. More →

Recent Health Tips

  • Ten Drugs Doctors Should Consider De-Prescribing

    Physicians use the word polypharmacy when a patient is taking five or more prescription drugs daily. A recent survey showed that half of women Medicare recipients were taking five or more drugs daily, and 12% of them were taking ten (!) or more. New patients frequently arrive at WholeHealth Chicago carrying bags stuffed like piñatas with prescription drugs and nutritional supplements, the latter recommended by Read More

  • Toxic Metals, Heart Disease, and Chelation Therapy

    In last week’s Health Tip I reviewed the well-researched health dangers of environmental toxic metals (also called heavy metals). They’ve always been a serious health risk, but with the Trump Administration’s recent rollbacks of clean air and water regulations we can expect even more trouble ahead. Statisticians predict an astonishing 160,000 unnecessary deaths over the next decade from the reversals of clean air and water Read More

  • Heavy Metal Toxicity and Your Health

    For those who were otherwise preoccupied that day long ago in high school chemistry, the heavy metals refer to a group of especially dense metals or metal-like substances (called metalloids) found in the environment. These metals–specifically lead, mercury, arsenic, cadmium, and aluminum–can all be absorbed by your body and stored there. Our environment is already quite toxic (Trump’s EPA deregulations aren’t helping) and it’s getting Read More

This month, save 20% off all Metagenics Medical Foods

UltraMeal
UltraInflamX
UltraClear